{"product_id":"ipamorelin","title":"Ipamorelin","description":"\u003cdiv class=\"strapi-description text-sm text-[#4B5563] md:text-base line-clamp-6\"\u003e\n\u003cp\u003eIpamorelin research compound. Supplied as a lyophilized peptide reference material for laboratory research applications.\u003c\/p\u003e\n\u003cp\u003eThis product is purity-tested for compound identity and is intended for in vitro experimentation, analytical reference, or scientific characterization studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"container px-3\"\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Characteristics\" id=\"characteristics\"\u003eCharacteristics\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolecular Formula\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eC38H49N9O5\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eCAS-number\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e170851-70-4\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolar Mass\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e711.86 g\/mol\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eChemical Formula\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eH-Aib-His-D-2-Nal-D-Phe-Lys-NH2\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eAmino Acid Sequence\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eAib-His-D-2-Nal-D-Phe-Lys\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSynonyms\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eNNC 26-0161, Ipamorelin acetate\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSolubility\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWater-soluble\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eOrganoleptic Profile\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWhite to off-white powder\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eComposition\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eLyophilized powder - requires reconstitution\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"How does Ipamorelin work?\" id=\"how-does-ipamorelin-work\"\u003eHow does Ipamorelin work?\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003cp\u003eIpamorelin is a selective agonist of the ghrelin receptor (GHS-R1a) and stimulates the release of growth hormone (GH) from the anterior pituitary gland. Unlike other GH secretagogues, Ipamorelin does not significantly increase levels of adrenocorticotropic hormone (ACTH), cortisol, or prolactin. This selectivity makes Ipamorelin a promising research peptide for studying the effects of GH secretion without the confounding effects of other hormones.\u003c\/p\u003e\n\u003cp\u003eIpamorelin binds to the GHS-R1a receptor, which is primarily expressed in the hypothalamus and pituitary gland. Upon binding, it triggers a cascade of signaling events that ultimately lead to the synthesis and secretion of GH. The released GH then binds to its receptors in various target tissues, such as the liver, muscle, and bone, to exert its anabolic effects.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Benefits\" id=\"benefits\"\u003eBenefits\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003cp\u003eBased on research studies, Ipamorelin has demonstrated several potential benefits in animal models:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cp\u003eGrowth hormone secretion: Ipamorelin potently stimulates the release of GH from the pituitary gland, which can help maintain or increase lean body mass, reduce body fat, and improve overall body composition.\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eAppetite regulation: Ipamorelin has been shown to regulate appetite and food intake in animal studies, suggesting its potential as a research tool in studying metabolic disorders and obesity.\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eBone health: GH plays a crucial role in maintaining bone mineral density and strength. Ipamorelin-induced GH secretion may have potential benefits for bone health, as demonstrated in animal studies.\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eCardiovascular function: Some studies have indicated that Ipamorelin may have positive effects on cardiovascular function, such as improving left ventricular function and reducing systemic vascular resistance in animal models.\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eAnti-aging effects: GH levels decline with age, contributing to age-related changes in body composition, bone density, and skin elasticity. Ipamorelin-induced GH secretion may help mitigate some of these age-related changes, as suggested by animal studies.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Side Effects\" id=\"side-effects\"\u003eSide Effects\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cp\u003eIn animal studies, Ipamorelin appeared to be well-tolerated with minimal side effects. \u003c\/p\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Summary\" id=\"summary\"\u003eSummary\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cp\u003eIpamorelin is a research peptide and selective ghrelin receptor agonist that stimulates the secretion of growth hormone (GH) from the pituitary gland. Animal studies have demonstrated its potential benefits in promoting GH release, regulating appetite, improving body composition, supporting bone health, and enhancing cardiovascular function. Ipamorelin's selectivity for GH secretion without significantly affecting other hormones makes it a promising research tool in the fields of endocrinology, metabolism, and aging. However, further research is needed to fully elucidate its mechanisms of action, potential therapeutic applications, and safety profile in mammalian models.\u003c\/p\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"References:\" id=\"references\"\u003eReferences:\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003col\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1530\/eje.0.1390552\"\u003eRaun, K., Hansen, B. S., Johansen, N. L., Thøgersen, H., Madsen, K., Ankersen, M., \u0026amp; Andersen, P. H. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1054\/ghir.1999.0096\"\u003eJohansen, P. B., Nowak, J., Skjaerbaek, C., Flyvbjerg, A., Andreassen, T. T., Wilken, M., \u0026amp; Ørskov, H. (1999). Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Hormone \u0026amp; IGF Research, 9(2), 106-113. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1210\/jcem.83.2.4539\"\u003eSvensson, J., Lönn, L., Jansson, J. O., Murphy, G., Wyss, D., Krupa, D., Cerchio, K., Polvino, W., Gertz, B., Boseaus, I., Sjöström, L., \u0026amp; Bengtsson, B. A. (1998). Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue increases GH secretion, fat-free mass, and energy expenditure. The Journal of Clinical Endocrinology \u0026amp; Metabolism, 83(2), 362-369. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9733495\/\"\u003eAnkersen, M., Johansen, N. L., Madsen, K., Hansen, B. S., Raun, K., Nielsen, K. K., Thøgersen, H., Hansen, T. K., Peschke, B., Lau, J., Lundt, B. F., \u0026amp; Andersen, P. H. (1999). A new series of highly potent growth hormone-releasing peptides derived from ipamorelin. Journal of Medicinal Chemistry, 42(19), 3699-3704. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1023\/a:1018955126402\"\u003eGobburu, J. V., Agerso, H., Jusko, W. J., \u0026amp; Ynddal, L. (1999). Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharmaceutical Research, 16(9), 1412-1416. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1530\/eje.0.1410180\"\u003eHansen, B. S., Raun, K., Nielsen, K. K., Johansen, P. B., Hansen, T. K., Peschke, B., Lau, J., Andersen, P. H., \u0026amp; Ankersen, M. (1999). Pharmacological characterisation of a new oral GH secretagogue, NN703. European Journal of Endocrinology, 141(2), 180-189. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1210\/jcem.83.4.4701\"\u003ePihoker, C., Kearns, G. L., French, D., \u0026amp; Bowers, C. Y. (1998). Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: A phase I study in children. The Journal of Clinical Endocrinology \u0026amp; Metabolism, 83(4), 1168-1172. \u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1210\/jcem.83.7.4969\"\u003eMericq, V., Cassorla, F., Salazar, T., Avila, A., Iñiguez, G., Bowers, C. Y., \u0026amp; Merriam, G. R. (1998). Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children. The Journal of Clinical Endocrinology \u0026amp; Metabolism, 83(7), 2355-2360.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/s000180050257\"\u003eBowers, C. Y. (1998). Growth hormone-releasing peptide. Cellular and Molecular Life Sciences (CMLS), 54(12), 1316-1329.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1530\/eje.0.1360445\"\u003eGhigo, E., Arvat, E., Muccioli, G., \u0026amp; Camanni, F. (1997). Growth hormone-releasing peptides. European Journal of Endocrinology, 136(5), 445-460.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/doi.org\/10.1210\/endo-114-5-1537\"\u003eBowers, C. Y., Momany, F. A., Reynolds, G. A., \u0026amp; Hong, A. (1984). On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology, 114(5), 1537-1545.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--$!--\u003e\u003ctemplate data-dgst=\"BAILOUT_TO_CLIENT_SIDE_RENDERING\"\u003e\u003c\/template\u003e\n  \u003cdiv data-scroll-name=\"Certificate of Analysis (COA)\" class=\"\"\u003e\n  \u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\n    \u003ch2 class=\"mb-6 text-2xl font-semibold leading-[2.25rem] tracking-tight md:my-0\" id=\"certificates\"\u003e\n      Certificate of Analysis (COA)\n    \u003c\/h2\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv class=\"flex w-full flex-row flex-wrap gap-x-0 gap-y-4 md:gap-x-8\"\u003e\n  \n    \u003cdiv class=\"w-1\/2 md:w-fit\"\u003e\n      \u003cdiv class=\"relative overflow-hidden rounded-none\"\u003e\n\t\t\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/Ipamorelin-1.avif?v=1779881016\" target=\"_blank\"\u003e\n        \u003cimg alt=\"Certificate\" loading=\"lazy\" width=\"175\" height=\"227\" decoding=\"async\" data-nimg=\"1\" class=\"h-full w-full max-w-[150px] cursor-pointer rounded-none object-cover md:max-w-[175px]\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/Ipamorelin-1.avif?v=1779881016\" style=\"color: transparent;\"\u003e\n\t\t\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n\t\n\t\u003cdiv class=\"w-1\/2 md:w-fit\"\u003e\n      \u003cdiv class=\"relative overflow-hidden rounded-none\"\u003e\n\t\t\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/Ipamorelin-2.avif?v=1779881015\" target=\"_blank\"\u003e\n        \u003cimg alt=\"Certificate\" loading=\"lazy\" width=\"175\" height=\"227\" decoding=\"async\" data-nimg=\"1\" class=\"h-full w-full max-w-[150px] cursor-pointer rounded-none object-cover md:max-w-[175px]\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/Ipamorelin-2.avif?v=1779881015\" style=\"color: transparent;\"\u003e\n\t\t\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n  \u003c!--\/$--\u003e\u003cdiv data-scroll-name=\"Resource\" class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" id=\"resources\"\u003eResource\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"w-full\"\u003e\u003cdiv class=\"text-base text-[#4B5563]\"\u003e\u003cspan\u003eAll products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.\u003c\/span\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"10mg","offer_id":53240040096044,"sku":"PEP-VIL-IPAMO-10MG955165","price":49.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/ipamorelin-1735841888165.png?v=1779696805","url":"https:\/\/www.powerpieeptidesus.com\/products\/ipamorelin","provider":"Power Peptides","version":"1.0","type":"link"}