{"product_id":"ptd-dbm","title":"PTD-DBM","description":"\u003cdiv class=\"strapi-description text-sm text-[#4B5563] md:text-base line-clamp-6\"\u003e\n\u003cp\u003ePTD-DBM research compound. Supplied as a lyophilized peptide reference material for laboratory research applications.\u003c\/p\u003e\n\u003cp\u003eThis product is purity-tested for compound identity and is intended for in vitro experimentation, analytical reference, or scientific characterization studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"container px-3\"\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Characteristics\" id=\"characteristics\"\u003eCharacteristics\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolecular Formula\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eC₁₂₄H₂₂₅N₆₁O₂₈S₂\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eCAS Number\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e120287-85-6 or 1609454-11-6\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolar Mass\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e3082.62 g\/mol\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eAmino Acid Sequence\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eArg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Gly-Arg-Lys-Thr-Gly-His-Gln-Ile-Cys-Lys-Phe-Arg-Lys-Cys\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSynonyms\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eProtein Transduction Domain-fused Dishevelled Binding Motif, Protein transduction domain (PTD)-Dvl-binding motif (DBM), Hair growth peptide, Follicle regeneration peptide\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSolubility\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWater-soluble\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eOrganoleptic Profile\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWhite to off-white powder\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eComposition\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eLyophilized powder - requires reconstitution\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"How is PTD-DBM Used in Research?\" id=\"how-is-ptd-dbm-used-in-research\"\u003eHow is PTD-DBM Used in Research?\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cp\u003ePTD-DBM peptide mechanism of action research suggests it may primarily function as a peptide inhibitor of the CXXC5-Dishevelled protein interaction, potentially activating the Wnt\/β-catenin signaling pathway. Current studies on ptd-dbm indicate the compound may demonstrate enhanced hair follicle regeneration properties through multiple potential molecular pathways. \u003cbr\u003e\u003cbr\u003eThe primary mechanism research suggests that ptd dbm peptide may involve the competitive binding to the Dishevelled (Dvl) protein, potentially preventing CXXC5 from inhibiting the Wnt\/β-catenin pathway. By disrupting this inhibitory interaction, ptd dbm may enhance downstream signaling involved in hair follicle development and regeneration through both direct and indirect cellular pathways.\u003cbr\u003e\u003cbr\u003eAdditionally, studies indicate PTD-DBM may have effects on wound-induced hair neogenesis (WIHN) and tissue regeneration. Research suggests it may stimulate stem cells in hair follicles and possibly enhance keratinocyte proliferation, potentially contributing to improved follicle cycling and hair growth phases.\u003cbr\u003eThe peptide's protein transduction domain (PTD) structure, consisting of eight arginine residues, may allow for enhanced cellular penetration, possibly leading to more consistent therapeutic effects when applied topically to affected areas.\u003cbr\u003e\u003cbr\u003eResearch also suggests potential synergistic effects when combined with compounds like valproic acid (VPA), which may further activate the Wnt\/β-catenin pathway through GSK3β inhibition. \u003cbr\u003eFor research institutions looking to buy ptd-dbm from a verified ptd-dbm peptide supplier, sourcing high-purity material with validated analytical data is critical to ensure experimental accuracy and reproducibility.\u003cbr\u003e \u003c\/p\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Areas of Study\" id=\"areas-of-study\"\u003eAreas of Study\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Follicle Regeneration\u003c\/strong\u003e:  Research on ptd-dbm peptide suggests it may have potential effects on new hair follicle formation and may help prevent follicle miniaturization studied in laboratory research. Studies investigating ptd dbm indicate its mechanism targeting the CXXC5–Dvl interaction may support activation of the Wnt\/β-catenin pathway, which plays a key role in follicular development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing\u003c\/strong\u003e: Studies indicate ptd-dbm may improve cutaneous wound healing and may offer potential benefits for tissue regeneration and collagen synthesis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtended Effects\u003c\/strong\u003e: Research suggests hair growth may be maintained even after treatment cessation, potentially indicating sustained follicle activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStem Cell Activation\u003c\/strong\u003e: Studies suggest it may have effects on follicle stem cell populations, potentially contributing to enhanced anagen phase duration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination Potential\u003c\/strong\u003e: Research indicates there may be possible synergistic effects when ptd-dbm is combined with other therapeutic agents like valproic acid or microneedling procedures.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Summary\" id=\"summary\"\u003eSummary\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cp\u003ePTD-DBM may represent an advancement in peptide-based hair regeneration research, in laboratory research contexts. Its unique structure targeting the CXXC5-Dvl interaction may provide a novel approach to activating hair growth pathways while potentially maintaining beneficial effects even after treatment discontinuation. Current investigations indicate that ptd-dbm may have promising research applications in both hair loss prevention and active follicle regeneration. Ongoing studies are also exploring broader regenerative potential, including wound healing and tissue repair models.\u003c\/p\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"References\" id=\"references\"\u003eReferences\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003col\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28595998\/\"\u003eLee SH, Seo SH, Lee DH, Pi LQ, Lee WS, Choi KY. Targeting of CXXC5 by a Competing Peptide Stimulates Hair Regrowth and Wound-Induced Hair Neogenesis. Journal of Investigative Dermatology. 2017 Nov;137(11):2260-2269. doi: 10.1016\/j.jid.2017.04.038. PMID: 28942361.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26056233\/\"\u003eLee SH, Kim MY, Kim HY, Lee YM, Kim H, Nam KA, Roh MR, Min do S, Chung KY, Choi KY. The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing. J Exp Med. 2015 Jun 29;212(7):1061-80. doi: 10.1084\/jem.20141601. Epub 2015 Jun 8. PMID: 26056233; PMCID: PMC4493411.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.mdpi.com\/2073-4409\/12\/4\/555\"\u003eRyu, Y.C.; Park, J.; Kim, Y.-R.; Choi, S.; Kim, G.-U.; Kim, E.; Hwang, Y.; Kim, H.; Han, G.; Lee, S.-H.; et al. CXXC5 Mediates DHT-Induced Signaling via PGD2. Cells 2023, 12, 555. https:\/\/doi.org\/10.3390\/cells12040555\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22506014\/\"\u003eLee SH, Yoon J, Shin SH, Zahoor M, Kim HJ, Park PJ, Park WS, Min do S, Kim HY, Choi KY. Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells. PLoS One. 2012;7(4):e34152. doi: 10.1371\/journal.pone.0034152. Epub 2012 Apr 10. PMID: 22506014; PMCID: PMC3323655.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10750333\/\"\u003eLiu D, Xu Q, Meng X, Liu X, Liu J. Status of research on the development and regeneration of hair follicles. Int J Med Sci. 2024 Jan 1;21(1):80-94. doi: 10.7150\/ijms.88508. PMID: 38164355; PMCID: PMC10750333.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--$!--\u003e\u003ctemplate data-dgst=\"BAILOUT_TO_CLIENT_SIDE_RENDERING\"\u003e\u003c\/template\u003e\n  \u003cdiv data-scroll-name=\"Certificate of Analysis (COA)\" class=\"\"\u003e\n  \u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\n    \u003ch2 class=\"mb-6 text-2xl font-semibold leading-[2.25rem] tracking-tight md:my-0\" id=\"certificates\"\u003e\n      Certificate of Analysis (COA)\n    \u003c\/h2\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv class=\"flex w-full flex-row flex-wrap gap-x-0 gap-y-4 md:gap-x-8\"\u003e\n  \n    \u003cdiv class=\"w-1\/2 md:w-fit\"\u003e\n      \u003cdiv class=\"relative overflow-hidden rounded-none\"\u003e\n\t\t\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/PTD-DBM.avif?v=1779874912\" target=\"_blank\"\u003e\n        \u003cimg alt=\"Certificate\" loading=\"lazy\" width=\"175\" height=\"227\" decoding=\"async\" data-nimg=\"1\" class=\"h-full w-full max-w-[150px] cursor-pointer rounded-none object-cover md:max-w-[175px]\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/PTD-DBM.avif?v=1779874912\" style=\"color: transparent;\"\u003e\n\t\t\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n  \u003c!--\/$--\u003e\u003cdiv data-scroll-name=\"Resource\" class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" id=\"resources\"\u003eResource\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"w-full\"\u003e\u003cdiv class=\"text-base text-[#4B5563]\"\u003e\u003cspan\u003eAll products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.\u003c\/span\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"10mg","offer_id":53240042815788,"sku":"PEP-VIL-PTDDBM-10MG369652","price":94.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/ptd-dbm-website-card-1747916617664.png?v=1779696850","url":"https:\/\/www.powerpieeptidesus.com\/products\/ptd-dbm","provider":"Power Peptides","version":"1.0","type":"link"}