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BPC-157 + TB-500 5mg/5mg (10mg Blend)
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DETAILS
Multi-peptide research blend. Multiple lyophilized peptide compounds supplied as a combined preparation for laboratory research applications.
Purity-tested per lot. Intended for in vitro experimentation or analytical reference studies.
For laboratory research use only. Not for human or veterinary use.
Characteristics
|
Molecular Formula |
C98H144N28O32 (BPC-157), C212H350N56O78S (TB-500) |
|
CAS Number |
137525-51-0 (BPC-157), 77591-33-4 (TB-500) |
|
Molar Mass |
2188.34 g/mol (BPC-157), 4963.46 g/mol (TB-500) |
|
Amino Acid Sequence |
BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, TB-500: Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
|
Synonyms |
Body Protection Compound-157, Thymosin β-4 |
|
Solubility |
Water-soluble |
|
Organoleptic Profile |
White lyophilized powder |
|
Composition |
Blend of BPC-157 and TB-500 peptides |
How does BPC-157 and TB-500 blend work?
BPC-157 and TB-500 each have unique mechanisms of action that contribute to their combined effects. BPC-157 has been shown to promote angiogenesis, stimulate collagen synthesis, and modulate the nitric oxide (NO) system, which plays a crucial role in wound healing and tissue regeneration. Additionally, BPC-157 exhibits anti-inflammatory properties by modulating the activity of inflammatory mediators such as cytokines and free radicals.
TB-500, on the other hand, is involved in the regulation of actin polymerization, a process essential for cell migration and tissue repair. It also promotes keratinocyte and endothelial cell migration, facilitating wound healing and angiogenesis. Furthermore, TB-500 has been shown to downregulate inflammatory cytokines, contributing to its anti-inflammatory effects.
When combined, BPC-157 and TB-500 work synergistically to enhance the body's natural healing processes. They promote the formation of new blood vessels, improve collagen synthesis, reduce inflammation, and support the migration and differentiation of cells involved in tissue repair.
Benefits
The BPC-157 and TB-500 blend offers a wide range of potential benefits for researchers investigating wound healing, tissue regeneration, and recovery. Some of the key benefits include:
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Enhanced wound healing: The combination of BPC-157 and TB-500 has been shown to accelerate the healing of various types of wounds, including skin, muscle, and tendon injuries.
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Improved tissue regeneration: This peptide blend promotes the regeneration of damaged tissues by stimulating angiogenesis, collagen synthesis, and cell migration.
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Reduced inflammation: Both BPC-157 and TB-500 exhibit anti-inflammatory properties, helping to modulate the inflammatory response and reduce swelling and pain associated with injuries.
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Neuroprotective effects: Studies have suggested that BPC-157 may have neuroprotective properties, potentially supporting brain health and recovery from neurological injuries.
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Cardiovascular support: The angiogenic properties of BPC-157 and TB-500 may contribute to improved cardiovascular health by promoting the formation of new blood vessels and supporting circulation.
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Musculoskeletal benefits: This peptide combination has shown promise in supporting the healing and recovery of muscles, tendons, and ligaments, making it an attractive option for researchers investigating musculoskeletal disorders and injuries.
Side Effects
Based on the available research, BPC-157 and TB-500 appear to be well-tolerated with minimal side effects. However, as with any experimental compound, caution should be exercised, and further research is needed to fully understand the potential risks and side effects associated with this peptide blend. Some possible side effects may include:
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Injection site reactions: Local irritation, redness, or swelling at the injection site may occur.
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Headaches: Some individuals may experience headaches, particularly during the initial stages of use.
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Gastrointestinal issues: In rare cases, gastrointestinal discomfort, such as nausea or diarrhea, may be reported.
Summary
The BPC-157 and TB-500 blend is a promising combination of peptides that offers a wide range of potential benefits for researchers investigating wound healing, tissue regeneration, and recovery. By working synergistically, these peptides promote angiogenesis, collagen synthesis, cell migration, and exhibit anti-inflammatory properties. While the available research suggests that this peptide blend is well-tolerated with minimal side effects, further studies are needed to fully understand its long-term safety and efficacy. As a versatile tool for researchers, the BPC-157 and TB-500 blend may open new avenues for the development of innovative therapies targeting various health conditions, including musculoskeletal injuries, neurological disorders, and cardiovascular diseases.
References
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Chang, C. H., Tsai, W. C., Lin, M. S., Hsu, Y. H., & Pang, J. H. S. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 110(3), 774-780. https://pubmed.ncbi.nlm.nih.gov/21030672/
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Huang, T., Zhang, K., Sun, L., Xue, X., Zhang, C., Shu, Z., ... & Pang, J. (2015). Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Design, Development and Therapy, 9, 2485. https://pubmed.ncbi.nlm.nih.gov/25995620/
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Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D. S., Brcic, L., ... & Vlainic, J. (2014). Stable gastric pentadecapeptide BPC 157-NO-system relation. Current Pharmaceutical Design, 20(7), 1126-1135. https://pubmed.ncbi.nlm.nih.gov/23755725/
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Philp, D., Kleinman, H. K., & Goldblatt, P. J. (2010). Thymosin β4 and the potential for therapeutic applications. Expert Opinion on Biological Therapy, 10(1), 149-158. https://pubmed.ncbi.nlm.nih.gov/20001564/
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Sosne, G., Qiu, P., Goldstein, A. L., & Wheater, M. (2010). Biological activities of thymosin β4 defined by active sites in short peptide sequences. The FASEB Journal, 24(7), 2144-2151. https://pubmed.ncbi.nlm.nih.gov/20179146/
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Hsieh, M. J., Liu, H. T., Wang, C. N., Huang, H. Y., Lin, Y., Ko, Y. S., ... & Pang, J. H. S. (2017). Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine, 95(3), 323-333. https://pubmed.ncbi.nlm.nih.gov/27847966/
Resource
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