{"product_id":"tb-500","title":"TB-500","description":"\u003cdiv class=\"strapi-description text-sm text-[#4B5563] md:text-base line-clamp-6\"\u003e\n\u003cp\u003eTB-500 research compound, also known as Thymosin Beta-4 Fragment. Supplied as a lyophilized peptide reference material for laboratory research applications.\u003c\/p\u003e\n\u003cp\u003eThis product is purity-tested for compound identity and is intended for in vitro experimentation, analytical reference, or scientific characterization studies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only. Not for human or veterinary use.\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"container px-3\"\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"TB-500 Characteristics\" id=\"tb-500-characteristics\"\u003eTB-500 Characteristics\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolecular Formula\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eC212H350N56O78S\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eCAS\tNumber\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e77591-33-4\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eMolar Mass\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003e4963.4 g\/mol\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eAmino Acid Sequence\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eSer-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSynonyms\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eThymosin Beta-4, Tβ4, TMSB4X, PTMB4, TB500\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eSolubility\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWater-soluble\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eOrganoleptic Profile\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eWhite to off-white powder\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cp\u003eComposition\u003c\/p\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cp\u003eLyophilized powder - requires reconstitution\u003c\/p\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"What is TB-500 and How does it work?\" id=\"what-is-tb-500-and-how-does-it-work\"\u003eWhat is TB-500 and How does it work?\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003cp\u003eTB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide conserved across species and expressed in various tissues. Research has shown that TB-500 interacts with actin, a protein crucial for cell migration and tissue remodeling. This interaction promotes actin polymerization, which is essential for angiogenesis and cell migration to injury sites.\u003c\/p\u003e\n\u003cp\u003eStudies have demonstrated that TB-500 modulates the expression of genes involved in inflammation, wound healing, and tissue regeneration. For instance, it has been found to upregulate matrix metalloproteinases (MMPs), enzymes key to extracellular matrix remodeling and wound healing.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"TB-500 Peptide Benefits and Research Findings\" id=\"tb-500-peptide-benefits-and-research-findings\"\u003eTB-500 Peptide Benefits and Research Findings\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003cp\u003eResearch in mammalian models has revealed:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWound healing: TB-500 has been shown to enhance keratinocyte and fibroblast migration, stimulate angiogenesis, and reduce inflammation, contributing to faster healing in various wound types.\u003c\/li\u003e\n\u003cli\u003eAnti-inflammatory effects: Studies have demonstrated TB-500's ability to reduce pro-inflammatory cytokine production and increase anti-inflammatory cytokine levels in various inflammatory conditions.\u003c\/li\u003e\n\u003cli\u003eHair growth stimulation: Research using mammalian models has found that TB-500 can increase hair follicle size and promote the transition from telogen to anagen phase.\u003c\/li\u003e\n\u003cli\u003eNeuroprotection: Studies have explored TB-500's potential to reduce neuroinflammation, oxidative stress, and apoptosis in models of neurological disorders.\u003c\/li\u003e\n\u003cli\u003eCardioprotection: In mammalian models of myocardial infarction, TB-500 has been shown to reduce infarct size, improve cardiac function, and promote angiogenesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese TB-500 peptide benefits make it an important subject of ongoing research in tissue repair and cellular recovery.\u003c\/p\u003e\n\u003cp\u003eWhile these findings are promising, it is important to note that TB-500 is currently a research tool, and its effects in mammals are still being studied.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"TB-500 Side Effects\" id=\"tb-500-side-effects\"\u003eTB-500 Side Effects\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\u003cul\u003e\n\u003cli\u003e\u003cp\u003eInjection site reactions (pain, redness, swelling)\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eHeadache\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eNausea\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eDizziness\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003eFatigue\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"Summary\" id=\"summary\"\u003eSummary\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003cp\u003eTB-500, a synthetic version of the naturally occurring peptide Thymosin Beta-4, has shown remarkable potential in various research settings. The peptide has been extensively studied for its ability to promote wound healing, reduce inflammation, stimulate hair growth, provide neuroprotection, and offer cardioprotection. TB-500 exerts its effects through multiple mechanisms, including its interaction with actin, modulation of gene expression, and regulation of inflammatory pathways. \u003c\/p\u003e\n\u003cp\u003eAs a research tool, TB-500 offers a valuable opportunity to explore the complex mechanisms underlying wound healing, inflammation, and tissue regeneration. The insights gained from these studies may pave the way for the development of novel therapeutic strategies for a wide range of conditions, from skin wounds and hair loss disorders to neurodegenerative diseases and cardiovascular disorders.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" data-scroll-name=\"References\" id=\"references\"\u003eReferences\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"strapi-content max-w-none text-[#4B5563]\"\u003e\n\u003col\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36709593\/\"\u003eBock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F Jr, Olson EN, Srivastava D. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. Int Immunopharmacol. 2023 Mar;116:109741. doi: 10.1016\/j.intimp.2023.109741. Epub 2023 Jan 27. PMID: 36709593.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29508629\/\"\u003eBelsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. Thymosin beta 4 regulation of actin in sepsis. Expert Opin Biol Ther. 2018 Jul;18(sup1):193-197. doi: 10.1080\/14712598.2018.1448381. Epub 2018 Mar 6. PMID: 29508629; PMCID: PMC6556887.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12852258\/\"\u003eBubb MR. Thymosin beta 4 interactions. Vitam Horm. 2003;66:297-316. doi: 10.1016\/s0083-6729(03)01008-2. PMID: 12852258.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30063853\/\"\u003eSosne G. Thymosin beta 4 and the eye: the journey from bench to bedside. Expert Opin Biol Ther. 2018 Jul;18(sup1):99-104. doi: 10.1080\/14712598.2018.1486818. PMID: 30063853.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27450736\/\"\u003ePipes GT, Yang J. Cardioprotection by Thymosin Beta 4. Vitam Horm. 2016;102:209-26. doi: 10.1016\/bs.vh.2016.04.004. Epub 2016 May 31. PMID: 27450736.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31877278\/\"\u003eSong K, Han HJ, Kim S, Kwon J. Thymosin beta 4 attenuates PrP(106-126)-induced human brain endothelial cells dysfunction. Eur J Pharmacol. 2020 Feb 15;869:172891. doi: 10.1016\/j.ejphar.2019.172891. Epub 2019 Dec 23. PMID: 31877278.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36834849\/\"\u003eChoi J, Cho Y, Choi H, Lee S, Han H, Lee J, Kwon J. Thymosin Beta 4 Inhibits LPS and ATP-Induced Hepatic Stellate Cells via the Regulation of Multiple Signaling Pathways. Int J Mol Sci. 2023 Feb 8;24(4):3439. doi: 10.3390\/ijms24043439. PMID: 36834849; PMCID: PMC9959661.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27450733\/\"\u003eKim J, Jung Y. Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells. Vitam Horm. 2016;102:121-49. doi: 10.1016\/bs.vh.2016.04.011. Epub 2016 May 31. PMID: 27450733.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30552633\/\"\u003eHan HJ, Kim S, Kwon J. Thymosin beta 4-Induced Autophagy Increases Cholinergic Signaling in PrP (106-126)-Treated HT22 Cells. Neurotox Res. 2019 Jul;36(1):58-65. doi: 10.1007\/s12640-018-9985-0. Epub 2018 Dec 15. PMID: 30552633.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26006229\/\"\u003eKim J, Jung Y. Potential role of thymosin Beta 4 in liver fibrosis. Int J Mol Sci. 2015 May 8;16(5):10624-35. doi: 10.3390\/ijms160510624. PMID: 26006229; PMCID: PMC4463665.\u003c\/a\u003e\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--$!--\u003e\u003ctemplate data-dgst=\"BAILOUT_TO_CLIENT_SIDE_RENDERING\"\u003e\u003c\/template\u003e\n  \u003cdiv data-scroll-name=\"Certificate of Analysis (COA)\" class=\"\"\u003e\n  \u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\n    \u003ch2 class=\"mb-6 text-2xl font-semibold leading-[2.25rem] tracking-tight md:my-0\" id=\"certificates\"\u003e\n      Certificate of Analysis (COA)\n    \u003c\/h2\u003e\n  \u003c\/div\u003e\n\n  \u003cdiv class=\"flex w-full flex-row flex-wrap gap-x-0 gap-y-4 md:gap-x-8\"\u003e\n  \n    \u003cdiv class=\"w-1\/2 md:w-fit\"\u003e\n      \u003cdiv class=\"relative overflow-hidden rounded-none\"\u003e\n\t\t\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/TB-500.avif?v=1779878617\" target=\"_blank\"\u003e\n        \u003cimg alt=\"Certificate\" loading=\"lazy\" width=\"175\" height=\"227\" decoding=\"async\" data-nimg=\"1\" class=\"h-full w-full max-w-[150px] cursor-pointer rounded-none object-cover md:max-w-[175px]\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/TB-500.avif?v=1779878617\" style=\"color: transparent;\"\u003e\n\t\t\u003c\/a\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n  \u003c!--\/$--\u003e\u003cdiv data-scroll-name=\"Resource\" class=\"\"\u003e\n\u003cdiv class=\"md:w-[30%] md:min-w-[30%]\"\u003e\u003ch2 class=\"mb-4 scroll-mt-20 text-2xl font-semibold leading-[2rem] tracking-tight md:scroll-mt-24\" id=\"resources\"\u003eResource\u003c\/h2\u003e\u003c\/div\u003e\n\u003cdiv class=\"w-full\"\u003e\u003cdiv class=\"text-base text-[#4B5563]\"\u003e\u003cspan\u003eAll products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. Power Peptides is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Power Peptides is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption. Power Peptides Products are intended strictly for research purposes only. These products are not approved by the U.S. Food and Drug Administration (FDA) for human consumption or medical use. Under no circumstances should these peptides be used for any purpose other than research. By purchasing or using our peptides, you acknowledge and agree that you will use them solely in accordance with applicable laws and regulations and that you accept full responsibility for their use. Statements made on this website have not been evaluated by the USA Food and Drug Administration.\u003c\/span\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"10mg","offer_id":53240040816940,"sku":"PEP-VIL-TB500-10MG909968","price":81.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0971\/5731\/6908\/files\/tb-500-1735841614087.png?v=1779696814","url":"https:\/\/www.powerpieeptidesus.com\/products\/tb-500","provider":"Power Peptides","version":"1.0","type":"link"}